Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-02-10
1997-01-21
Ivy, C. Warren
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514277, 514357, 546293, 546294, 546338, 546339, C07D21334, A61K 3144
Patent
active
055960081
ABSTRACT:
A class of substitute pyridyl compounds is described for use in treating inflammation and inflammation-related disorders. Compounds of particular interest are defined by Formula I ##STR1## wherein R.sup.1 is haloalkyl; wherein R.sup.2 is aryl optionally substituted at a substitutable position with one or more radicals independently selected from alkylsulfinyl, alkyl, cyano, carboxyl, alkoxycarbonyl, haloalkyl, hydroxyl, hydroxyalkyl, haloalkoxy, amino, alkylamino, arylamino, nitro, halo, alkoxy and alkylthio; wherein R.sup.3 is aryl substituted at a substitutable position with a radical selected from alkylsulfonyl and sulfamyl; and wherein R.sup.4 is selected from halo, alkoxy and alkynyloxy; or a pharmaceutically-acceptable salt thereof.
REFERENCES:
patent: 3655679 (1972-04-01), Shen et al.
patent: 4011328 (1977-03-01), Pinhas et al.
patent: 5004743 (1991-04-01), Young et al.
patent: 5169857 (1992-12-01), Angerbauer et al.
Bulock Joseph W.
G. D. Searle & Co.
Ivy C. Warren
Smith Lyman H.
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