3,4-diamino-1,2,5-thiadiazole-1-oxides having histamine H.sub.1

Details 3,4-diamino-1,2,5-thiadiazole-1-oxides having histamine H.sub.1 3,4-diamino-1,2,5-thiadiazole-1-oxides having histamine H.sub.1

1986-06-11

1988-09-13

Fan, Jane T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514338, 514333, 514256, 546277, 546270, 546256, 544333, C07D41712, A61K 3144

Patent

active

047710586

ABSTRACT:
The invention relates to a class of 3,4-diamino-1,2,5-thiadiazole-1-oxides which have histamine H.sub.1 -antagonist activity. A preferred compound of the invention is 3-[3-(5-bromo-3-methylpyrid-2-ylamino)-propylamino]-4-amino-1,2,5-thiadiaz ole-1-oxide.

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patent: 4548940 (1985-10-01), Ife
patent: 4692456 (1987-09-01), Ufe

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