3,4-(cyclopentyl)-fused proline compounds as inhibitors of...

Details 3,4-(cyclopentyl)-fused proline compounds as inhibitors of... 3,4-(cyclopentyl)-fused proline compounds as inhibitors of...

2008-03-11

2008-03-11

Anderson, Rebecca (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C544S143000, C544S295000, C544S357000, C544S373000, C546S200000, C546S277100, C548S181000, C548S235000, C548S537000, C549S059000, C549S473000

Reexamination Certificate

active

07342041

ABSTRACT:
The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.

REFERENCES:
patent: 6608027 (2003-08-01), Tsantrizos et al.
patent: 1 157 998 (2001-11-01), None
patent: WO 98/22496 (1998-05-01), None
patent: WO 99/07734 (1999-02-01), None
patent: WO 00/09543 (2000-02-01), None
patent: WO 00/09558 (2000-02-01), None
patent: WO 00/59929 (2000-10-01), None
patent: WO 01/74768 (2001-10-01), None
patent: WO 01/77113 (2001-10-01), None
patent: WO 01/81325 (2001-11-01), None
patent: WO 02/08187 (2002-01-01), None
patent: WO 02/08244 (2002-01-01), None
patent: WO 02/08244 (2002-01-01), None
patent: WO 02/08256 (2002-01-01), None
patent: WO 08/08251 (2002-01-01), None
patent: WP 02/08198 (2002-01-01), None
patent: WO 02/18369 (2002-03-01), None
patent: WO 02/48172 (2002-06-01), None
patent: WO 03/062265 (2003-07-01), None
U.S. Appl. No. 10/052,386, filed Jan. 18, 2002.
Han, Wei, et al., “Alpha-Ketoamides, Alpha-Ketoesters and Alpha-Diketones . . . ,” Bioorganic & Medicinal Chemistry Letters 10:711-713 (2000).
Landro, James A., et al., “Mechanistic Role of an NS4A . . . ,” Biochemistry 36:9340-9348 (1997).
Marchetti, Antonella, et al., “Synthesis of Two Novel . . . ,” Synlett S1:1000-1002 (1999).
PCT International Search Report dated Jul. 29, 2005 for corresponding PCT Application No. PCT/US2005/005778.
Chen, Shu-Hui, et al., “Synthesis and Evaluation . . . ,” Bioorganic & Medicinal Chemistry Letters 3531-36 (2003).
Lamar, Jason, et al., “Novel P4 truncated . . . ,” Bioorganic & Medicinal Chemistry Letters 14:263-66 (2004).
Smith, R.M., et al., “Structure-based design . . . ,” Journal of Viral Hepatitis 10:405-412 (2003).

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