3-(4-Alkoxycarbonylpiperazin-1-yl)-sydnonimines, a process for t

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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544367, C07D41304, A61K 3141

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active

045514542

ABSTRACT:
Pharmacologically-active 3-aminosydnonimines (which are optionally substituted in the N.sup.6 -position) and their physiologically-acceptable acid-addition salts are compounded into standard dosage-form medicament compositions and are useful for prophylaxis for and treatment of cardiovascular-system disorders, such as high blood pressure and angina pectoris. The 3-aminosydnonimines are 3-[4-(lower alkoxy)carbonylpiperazin-1-yl]sydnonimines and 3-[N-(lower alkyl)-N-(tetrahydro-3-thienyl S,S-dioxide)]-sydnonimines.

REFERENCES:
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patent: 3833589 (1974-09-01), Simpson
patent: 4421754 (1983-12-01), Hidaka et al.
patent: 4430342 (1984-02-01), Hidaka et al.
patent: 4436743 (1984-03-01), Schonafinger et al.
patent: 4452797 (1984-06-01), Schonafinger et al.

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