3,4,5-substituted benzoylguanidines, process for their preparati

Details 3,4,5-substituted benzoylguanidines, process for their preparati 3,4,5-substituted benzoylguanidines, process for their preparati

1995-05-26

1997-12-02

Davis, Zinna Northington

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

514522, 514603, 514634, 514821, 564 86, 564162, 564237, C07C27922, A61K 3118, A61K 31155

Patent

active

056936729

ABSTRACT:
3,4,5-Substituted benzoylguanidines, process for their preparation, their use as a medicament or diagnostic and medicament containing them
Benzoylguanidines of the formula I ##STR1## where R(1) is R(4)--SO.sub.m or R(5)R(6)N--SO.sub.2 --, where R(4) and R(5) are alk(en)yl, --C.sub.n H.sub.2n --R(7), and where R(7) is cycloalkyl or phenyl, where R(5) is also H, R(6) is H or C.sub.1 --C.sub.4 --alkyl,
R(2) is hydrogen, (cyclo)-alk(en)(yn)yl, aryl and hetaryl,
R(3) is defined as R(2)
and their pharmaceutically tolerable salts are described.

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