3,3-neotrehalosadiamine antibiotic and producing it with novel m

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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536 187, 536 55, 536 172, 514 25, 424116, C07G 1100, C07H 1500, C07H 1700, A61K 3500

Patent

active

047329769

ABSTRACT:
3,3'-Neotrehalosadiamine antibiotic is prepared by fermentation of B. pumilus K169-B91 (ATCC No. 53206) in a nutrient medium preferably comprising soybean meal, corn starch, calcium carbonate and magnesium sulfate. The antibiotic and pharmaceutically acceptable salts and hydrates thereof and compositions containing these are useful to treat bacterial infections in mammals.

REFERENCES:
patent: 4260683 (1981-04-01), Kawaguchi et al.
patent: 4276412 (1981-06-01), Dolak et al.
patent: 4482707 (1984-04-01), Sakakibara et al.
Dolak et al.; J. Antibiotics 33:690-694 (1980).
Naganawa et al.; J. Antibiotics 27:145-146 (1974).
Uramoto et al.; J. Antibiotics 20A:236-237 (1967).

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