3,3'-disubstituted-1,3-dihydro-2H-pyrrolo[2,3-b]heterocyclic-2-o

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514254, 514255, 514256, 514269, 514300, 544238, 544298, 544322, 544333, 544336, 544405, 546113, A61K 3150, A61K 31505, A61K 3144, C07D47104

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active

052781623

ABSTRACT:
Compounds of Formula I have been shown to enhance the release of the neurotransmitters acetylcholine, dopamine and serotonin; and thus may be useful in the treatment of diseases of man where subnormal levels of this neurochemical are found such as in Alzheimer's disease and other conditions involving learning and cognition; and Parkinson's disease.
The compounds of this invention can be described as shown in Formula I ##STR1## where A is a heteroaromatic system.

REFERENCES:
patent: 4760083 (1988-07-01), Myers et al.
patent: 4997954 (1991-03-01), Fortunak
patent: 5006537 (1991-04-01), Effland et al.

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