3,3-diphenylpropylamines, their use and preparation

Details 3,3-diphenylpropylamines, their use and preparation 3,3-diphenylpropylamines, their use and preparation

1995-05-05

1996-09-24

Hamilton, III, Thomas

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

A61K 31135

Patent

active

055592694

ABSTRACT:
The invention relates to 3,3-diphenylpropylamines of formula (I), wherein R.sup.1 signifies hydrogen or methyl, R.sup.2 and R.sup.3 independently signify hydrogen, methyl, methoxy, hydroxy, carbamoyl, sulphamoyl or halogen, and X represents a tertiary amino group of formula (II), wherein R.sup.4 and R.sup.5 signify non-aromatic hydrocarbyl groups, which may be the same or different and which together contain at least three carbon atoms, and wherein R.sup.4 and R.sup.5 may form a ring together with the amine nitrogen, their salts with physiologically acceptable acids and, when the compounds can be in the form of optical isomers, the racemic mixture and the individual enantiomers. The invention also relates to methods for their preparation, pharmaceutical compositions containing the novel compounds, and the use of the compounds for preparing drugs ##STR1##

REFERENCES:
patent: 4139537 (1979-02-01), Diamond et al.

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