3,3-diphenylpropylamines, their use and preparation

Details 3,3-diphenylpropylamines, their use and preparation 3,3-diphenylpropylamines, their use and preparation

1996-07-22

1997-11-11

Krass, Frederick

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514317, 514408, 514648, 546216, 546240, 546242, 546248, 548541, 548556, 548574, 548575, 548578, 564443, A61K 31135

Patent

active

056864647

ABSTRACT:
A 3,3-diphenylpropylamine of the formula I, or its physiologically acceptable acid salt thereof: ##STR1## wherein R.sup.1 represents hydrogen or methyl, R.sup.2 and R.sup.3 independently represent hydrogen, methyl, methoxy, hydroxy, carbamoyl, sulphamoyl or halogen, and X represents a tertiary amino group of formula II ##STR2## wherein R.sup.4 and R.sup.5 independently represent a hydroxy substituted or unsubstituted non-aromatic hydrocarbyl group which can join together to form a ring and which together contain at least three carbon atoms, wherein at least one of R.sup.4 and R.sup.5 is hydroxy substituted, is useful in treating acetylcholine-mediated disorders such as urinary incontinence.

REFERENCES:
patent: 5559269 (1996-09-01), Johansson et al.

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