Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Patent
1991-12-19
1995-01-17
Raymond, Richard L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
514620, 514648, 564 86, 564165, 564316, A61K 31135, A61K 31165, A61K 3118, C07C21762
Patent
active
053826000
ABSTRACT:
##STR1## Novel 3,3-diphenylpropylamines of formula (I) wherein R.sup.1 signifies hydrogen or methyl, R.sup.2, R.sup.3 and R.sup.4 independently signify hydrogen, methyl, methoxy, hydroxy, carbamoyl, sulphanoyl or halogen, and X represents a tertiary amino group -NR.sup.5, R.sup.6, wherein R.sup.5 and R.sup.6 signify non-aromatic hydrocarbyl groups, which may be the same or different and which together contain at least three carbon atoms, and which may form a ring together with the amine nitrogen, their salts with physiologically acceptable acids and, when the compounds can be in the form of optical isomers, the racemic mixture and the individual enantiomers, their use as drugs, especially as anticholinergic agents, their use for preparing an anticholinergic drug, pharmaceutical compositions containing the novel amines, and methods for preparing the same.
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Markaryan et al., Chemical Abstracts, vol. 97 (1982) 120105n.
Atwal et al., J. Med. Chem., vol. 30 (1987) pp. 627-365.
Strehlke et al., Chemical Abstracts, vol. 91 (1979) 107943r.
Glas Gunilla
Jonsson Nils A.
Mikiver Lembit
Moses Pinchas
Nilvebrant Lisbet
Pharmacia Aktiebolag
Raymond Richard L.
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