3,3-Dichloro-2-azetidinone derivatives having basic substituents

Details 3,3-Dichloro-2-azetidinone derivatives having basic substituents 3,3-Dichloro-2-azetidinone derivatives having basic substituents

1978-06-30

1979-03-20

Trousof, Natalie

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen in the nitrogen containing substituent

544359, 26032637, 546208, C07D41312

Patent

active

041455410

ABSTRACT:
Compounds having the formula ##STR1## wherein X is oxygen or sulfur; R.sub.1 is alkyl, cycloalkyl or aryl; R.sub.2 is a nitrogen containing heterocyclic group; A.sub.1 is a saturated bond or an alkylene group having 1 to 4 carbon atoms; and A.sub.2 is an alkylene group having 2 to 5 carbon atoms; have antiinflammatory activity.

REFERENCES:
patent: 3194801 (1965-07-01), Perelman
patent: 3481920 (1969-12-01), Hargrove
patent: 4064120 (1977-12-01), Krapcho et al.
Duren et al., "Tetrahedron Letters", No. 3 (1970) pp. 245-248.
Morimoto et al., "Chem Abstracts" vol. 84 No. 163,799r (1976).

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