3-(3,5-di-tert-butyl-4-hydroxy benzylidene)-2-pyrrolidone and su

Details 3-(3,5-di-tert-butyl-4-hydroxy benzylidene)-2-pyrrolidone and su 3-(3,5-di-tert-butyl-4-hydroxy benzylidene)-2-pyrrolidone and su

1986-04-23

1989-05-23

Springer, David B.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514425, 548542, 548543, A61K 3140, C07D207276, C07D20727

Patent

active

048331600

ABSTRACT:
3-(3,5-di-tert-butyl-4-hydroxy-benzylidene)-2-pyrrolidone and N-substituted derivatives thereof are described. The substituent includes alkyl, alkoxy, alkynyl phenyl-alkylene, hydroxy-alkylene and amino-alkylene. They are effective as an anti-inflammatory, analgesic and antithermic agent, and they have a low toxicity.

REFERENCES:
patent: 4581364 (1986-04-01), Weber et al.

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