Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Fungus – except allergen – or component thereof or substance...
Patent
1979-04-17
1980-09-23
Rotman, Alan L.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Fungus, except allergen, or component thereof or substance...
546272, 2602452T, C07D48704, A61K 3140
Patent
active
042243360
ABSTRACT:
Disclosed are 3-(2-aminoethylthio)-6-amido-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxy lic acids having the structure: ##STR1## wherein R.sup.1 is hydrogen or acyl. Such compounds as well as their pharmaceutically acceptable salt, ester and amide derivatives are useful as antibiotics. Also disclosed are processes for the preparation of such compounds, pharmaceutical compositions comprising such compounds and methods of treatment comprising administering such compounds and compositions when an antibiotic effect is indicated.
REFERENCES:
patent: 4123547 (1978-10-01), Christensen et al.
patent: 4150145 (1979-04-01), Christensen et al.
patent: 4168268 (1979-09-01), Datta et al.
patent: 4172144 (1978-10-01), Bouffard et al.
Christensen Burton G.
Guthikonda Ravindra N.
Johnston David B. R.
Schmitt Susan M.
Arno James A.
Levitt Julian S.
Merck & Co. , Inc.
Pfeiffer Hesna J.
Rotman Alan L.
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