Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1979-10-03
1981-07-28
Rotman, Alan L.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
424274, 2602452R, 546272, C07D48704, A61K 31395
Patent
active
042810027
ABSTRACT:
Disclosed are 3-(2-aminoethylthio)-6-amido-7-oxo-1-azabicyclo [3.2.0]hept-2-ene-2-carboxylic acids having the structure: ##STR1## wherein R.sup.1 is hydrogen or acyl. Such compounds as well as their pharmaceutically acceptable salt, ester and amide derivatives are useful as antibiotics. Also disclosed are processes for the preparation of such compounds, pharmaceutical compositions comprising such compounds and methods of treatment comprising administering such compounds and compositions when an antibiotic effect is indicated.
REFERENCES:
patent: 4123547 (1978-10-01), Christensen et al.
patent: 4150145 (1979-04-01), Christensen et al.
patent: 4168268 (1979-09-01), Datta et al.
patent: 4172144 (1979-10-01), Bouffard et al.
Christensen Burton G.
Guthikonda Ravindra N.
Johnston David B. R.
Schmitt Susan M.
Arno James A.
Merck & Co. , Inc.
Pfeiffer Hesna J.
Rotman Alan L.
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