3-(1H-tetrazol-5-yl)thieno[2,3-d]pyrimidin-4(3H)-ones

Details 3-(1H-tetrazol-5-yl)thieno[2,3-d]pyrimidin-4(3H)-ones 3-(1H-tetrazol-5-yl)thieno[2,3-d]pyrimidin-4(3H)-ones

1986-02-25

1988-08-02

Gerstl, Robert

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

544278, 548251, 549 57, 549 59, 549 68, C07D49504

Patent

active

047614749

ABSTRACT:
3-(1H-Tetrazol-5-yl)thieno[2,3-d]pyrimidin-4(3H)-ones useful as antiallergic agents are described herein. The compounds are prepared by cyclization of an appropriate substituted amidine using an alkali metal base. The reaction is carried out in an appropriate inert solvent.

REFERENCES:
patent: 4054656 (1977-10-01), Temple, Jr.
patent: 4159377 (1979-06-01), Temple, Jr.
patent: 4419357 (1983-12-01), Peet et al.
patent: 4644065 (1987-02-01), Vinogradoff
Bohm et al., Pharmazie, 38(2), 135, 136 (1983).
Conner et al., J. Med. Chem., 27, 528 (1984).
Haubold et al., Pharmazie, 38(4), 269 (1983).
Ried et al., Ann. Chem., 713, 143 (1968).
Schellhase et al., Pharmazie, 39(1), 19 (1984).
Shishoo et al., Indian J. Chem., 21B, 666 (1982).
Shishoo et al., J. Het. Chem., 21(2), 375 (1984).
Temple et al., J. Med. Chem., 22, 505 (1979).
Tinney et al., J. Med. Chem., 24, 878 (1981).

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