3-(1H-indazol-3-yl)-4-pyridinamines

Details 3-(1H-indazol-3-yl)-4-pyridinamines 3-(1H-indazol-3-yl)-4-pyridinamines

1991-05-06

1992-11-24

Fan, Jane T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514338, 546309, 546311, 546312, 546271, A61K 3144, C07D21336

Patent

active

051661632

ABSTRACT:
This invention relates to 3-(1H-indazol-3-yl)-4-pyridinamines of the formula ##STR1## where R.sub.1 is hydrogen, loweralkyl, arylalkyl or acyl; R.sub.2 is hydrogen, loweralkyl or arylalkyl; R.sub.3 is hydrogen, loweralkyl or aryl and X is hydrogen, halogen, nitro or amino or the pharmaceutically acceptable addition salts thereof, and where applicable, the geometric and optical isomers and racemic mixtures thereof. The compounds of this invention are useful as analgesics and as topical antiinflammatory agents for the treatment of various dermatoses.

REFERENCES:
patent: 4656184 (1987-04-01), Coquelet et al.

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