3-(1H-imidazol-1-ylmethyl)-2-(disubstitutedaminomethyl)indoles a

Details 3-(1H-imidazol-1-ylmethyl)-2-(disubstitutedaminomethyl)indoles a 3-(1H-imidazol-1-ylmethyl)-2-(disubstitutedaminomethyl)indoles a

1977-12-19

1979-02-20

Trousof, Natalie

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

26032612R, 2603265B, 26032685, 424273R, 424274, C07D40306

Patent

active

041408586

ABSTRACT:
N,N-dialkyl-3-[(phenylthio)methyl]-1H-indole-2-methanamines or 3-(1H-imidazol-1-ylmethyl)-N,N,-dimethyl-1H-indole-2-methanamines and acid addition salts thereof which are useful pharmacological agents, especially antifungals, are disclosed. The compounds can be produced by reacting a thiophenols or imidazoles with the appropriate 2-alkyl-1,2,3,4-tetrahydropyrrolo[3,4-b]indole.

REFERENCES:
patent: 3491114 (1970-01-01), Suh et al.
patent: 3931229 (1976-01-01), Zinnes et al.
Andreani et al. J. Chem. Soc. (London) Part C, 1970, pp. 1157-1161.
Decodts et al. Chem. Abst. 1968, vol. 69, No. 96376a.

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