3, 10, and 12a substituted tetracycline compounds

Details 3, 10, and 12a substituted tetracycline compounds 3, 10, and 12a substituted tetracycline compounds

2005-02-28

2010-11-02

McIntosh, III, Traviss C (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

3,10-dihydroxy-2-naphthacene carboxamide or derivative doai

C552S202000, C552S203000, C552S205000

Reexamination Certificate

active

07825105

ABSTRACT:
The present invention pertains to novel 3, 10, and/or 12a-substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.

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