3-(1'-Silyloxy-2'-hydroxyethyl)-4-hydroxy-6-oxohexanoic acid .ga

Details 3-(1'-Silyloxy-2'-hydroxyethyl)-4-hydroxy-6-oxohexanoic acid .ga 3-(1'-Silyloxy-2'-hydroxyethyl)-4-hydroxy-6-oxohexanoic acid .ga

1977-05-12

1978-07-25

Trousof, Natalie

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07D30720

Patent

active

041028996

ABSTRACT:
The present specification provides novel intermediates and novel processes for the synthesis of Thromboxane B.sub.2 (11a-homo-11a-oxa-PGF.sub.2.alpha.), its 15-epimer, and various carboxyl derivatives thereof. In particular, there are disclosed various bicyclic tetrahydrofuran-containing lactones useful in the above processes, and corresponding acyclic lactones.

REFERENCES:
patent: 3971826 (1976-07-01), Hess et al.

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