3-(1-Imidazolyl)-derivatives of 2,3-dihydro-4H-1-benzopyran

Details 3-(1-Imidazolyl)-derivatives of 2,3-dihydro-4H-1-benzopyran 3-(1-Imidazolyl)-derivatives of 2,3-dihydro-4H-1-benzopyran

1981-02-12

1982-08-03

Fan, Jane T.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

548336, C07D40504, A61K 3133, A61K 31415

Patent

active

043427758

ABSTRACT:
3-(1-imidazolyl)-derivatives of 2,3-dihydro-4H-1-benzopyran, such as, for instance, the compound 3-(1-imidazolyl)-2,3-dihydro-4H-1-benzopyran-4-one, are disclosed, as well as method of making same, and pharmaceutical compositions containing same. Also disclosed is a method of using such compounds to inhibit blood platelet aggregation, to increase total serum HDL cholesterol, to increase the ratio between .alpha.-lipoprotein and .beta.-lipoprotein total cholesterol, and/or of reducing total serum cholesterol or serum triglycerides.

REFERENCES:
patent: 4013673 (1977-03-01), Connor et al.
patent: 4116971 (1978-09-01), Strandtmann
patent: 4157984 (1979-06-01), Zilliken

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