3-(1'-Hydroxy-2'-hydroxyethyl)-4,6-dihydroxyhexanoic acid 4.gamm

Details 3-(1'-Hydroxy-2'-hydroxyethyl)-4,6-dihydroxyhexanoic acid 4.gamm 3-(1'-Hydroxy-2'-hydroxyethyl)-4,6-dihydroxyhexanoic acid 4.gamm

1977-05-12

1978-04-25

Jaisle, Cecilia M.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07D30732

Patent

active

040862470

ABSTRACT:
The present specification provides novel intermediates and novel processes for the synthesis of Thromboxane B.sub.2 11a-homo-11a-oxa-PGF.sub.2.alpha.), its 15-epimer, and various carboxyl derivatives thereof. In particular, there are disclosed various bicyclic tetrahydrofuran-containing lactones useful in the above processes, and corresponding acyclic lactones.

REFERENCES:
patent: 4001286 (1977-01-01), Bundy
patent: 4052552 (1977-10-01), Schneider

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