3(1-hydoxyethyl)azetidinone compounds and their production

Details 3(1-hydoxyethyl)azetidinone compounds and their production 3(1-hydoxyethyl)azetidinone compounds and their production

1991-01-17

1992-07-28

Berch, Mark L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549494, 549291, 560 38, 560 39, 560 41, 560170, 560250, 560253, C07D20508, C07D40706, C07D30752, C07D30930

Patent

active

051342316

ABSTRACT:
An amino acid compound of the formula: ##STR1## wherein R is a lower alkyl group, R.sub.1 is a hydrogen atom or a protecting group for carboxyl, R.sub.2 is a hydrogen atom, a protecting group for amino, an optionally substituted allyl group of the formula: ##STR2## (wherein R.sub.3 and R.sub.4 are each a hydrogen atom, a lower alkyl group or an aryl group), a beta-hydroxyethyl group in which the hydroxyl group is optionally protected, a formylmethyl group in which the formyl group is optionally protected, a carboxymethyl group in which the carboxyl group is protected or a 2-furylmethyl group and X is an optionally protected carboxyl group, a hydroxymethyl group in which the hydroxyl group is optionally protected or a substituted mercaptomethyl group of the formula:

REFERENCES:
patent: 3950357 (1976-04-01), Kahan et al.
patent: 4734497 (1988-03-01), Christensen
patent: 5081238 (1992-01-01), Shibasaki
Johnston Journal of the American Chemical Society, vol. 100, pp. 313-315, 1987.
Shih Heterocycles, vol. 21, No. 1, pp. 29-40, 1984.

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