3-[(1,3-Dithiin-5-yl)-acetamido]-cephalosporins and antibacteria

Details 3-[(1,3-Dithiin-5-yl)-acetamido]-cephalosporins and antibacteria 3-[(1,3-Dithiin-5-yl)-acetamido]-cephalosporins and antibacteria

1977-01-17

1978-05-09

Rizzo, Nicholas S.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

544 30, 544 27, C07D50136, A61K 31545

Patent

active

040887618

ABSTRACT:
The invention provides novel cephalosporins of the formula: ##STR1## in which R.sub.1 represents acetoxy, (5-methyl-1,3,4-thiadiazol-2-yl)-thio, (1-methyl-tetrazol-5-yl)-thio or [1-(2-hydroxyethyl)-tetrazol-5-yl]-thio and R.sub.2 represents carboxyl, or R.sub.1 represents pyridinio and R.sub.2 the carboxylato ion, and, when R.sub.2 represents carboxyl, their metal salts and addition salts with nitrogen-containing bases, which have useful antibacterial properties.

REFERENCES:
patent: 4007176 (1977-02-01), Berger et al.

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