3-(1,2,5,6-Tetrahydropyridin-3-yl)-phenols and their use in phar

Details 3-(1,2,5,6-Tetrahydropyridin-3-yl)-phenols and their use in phar 3-(1,2,5,6-Tetrahydropyridin-3-yl)-phenols and their use in phar

1981-12-09

1983-05-10

Ford, John M.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

546342, 546343, 546344, A61K 3144, C07D21170

Patent

active

043829422

ABSTRACT:
Novel 3-(1,2,5,6-tetrahydropyridin-3-yl)-phenols of the formula ##STR1## wherein X is selected from the group consisting of hydrogen and an acyl of an organic carboxylic acid of 2 to 7 carbon atoms, Y is selected from the group consisting of hydrogen and --OX, R is selected from the group consisting of hydrogen, alkyl of 1 to 5 carbon atoms optionally substituted with --OH, cycloalkylalkyl of 4 to 7 carbon atoms, alkenyl and alkynyl of 3 to 5 carbon atoms and aralkyl of 7 to 12 carbon atoms optionally substituted on the alkyl with --OH with the proviso that when R is hydrogen, X is hydrogen and their non-toxic, pharmaceutically acceptable acid addition salts having dopaminergic agonist and/or antagonist properties and their preparation.

REFERENCES:
patent: 2498431 (1950-02-01), Lee
patent: 4046901 (1977-09-01), Nedelec et al.
patent: 4072685 (1978-02-01), Nedelec et al.
patent: 4302462 (1981-11-01), Collins et al.

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