(2R)-2-[di(2-propyl)phosphonylmethoxy]-3-p-to luenesulfonyloxy-1

Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system

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Details

544243, 544244, 546 23, 558124, 558179, C07F 96521, C07F 96509, C07F 96506, C07F 940

Patent

active

051304279

ABSTRACT:
The invention relates to the new compound (2R)-2-[di(2-propyl)phosphonylmethoxy]-3-p-toluenesulfonyloxy-1-trimethyla cetoxypropane and the method of producing it. The compound may be used for producing (S)-N-(3-hydroxy-2-phosphonylmethoxypropyl) derivatives of the heterocyclic purine and pyrimidine bases of antiviral activity.

REFERENCES:
patent: 4968686 (1990-11-01), Townsend et al.
Webb, R. R. et al. Tetrahedron Letters, vol. 29, pp. 5475-5478 (1988).

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