2H-pyran-2,6-(3H)-dione derivatives with anti-allergic activity

Details 2H-pyran-2,6-(3H)-dione derivatives with anti-allergic activity 2H-pyran-2,6-(3H)-dione derivatives with anti-allergic activity

1986-09-10

1988-02-16

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

549231, A61K 3135, C07D30936

Patent

active

047256206

ABSTRACT:
Achiral compounds of a 2H-pyran-2,6(3H)-dione derivative of the formula ##STR1## or a pharmaceutically acceptable salt thereof, where R is --(CH.sub.2).sub.m OH or --CH((CH.sub.2).sub.n CH.sub.2 OH).sub.2 where m is 1-5 and n is 0-4. These compounds are useful in the treatment of allergic conditions.

REFERENCES:
patent: 4165365 (1979-08-01), Snader
Snader et al., J. Med. Chem., vol. 22, No. 6 (1979) pp. 1-158, 706-174.
Cramer et al., Journal of Medicinal Chemistry, vol. 22, No. 6 (1979) pp. 714-724.

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