2H-imidazole-2-thione derivatives

Details 2H-imidazole-2-thione derivatives 2H-imidazole-2-thione derivatives

1977-12-08

1979-08-28

Trousof, Natalie

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

260307A, 260558R, 260558P, 260584A, C07D23384

Patent

active

041661842

ABSTRACT:
Imidazole derivatives which are useful intermediates for the production of compounds having pharmacological activity at histamine H.sub.2 receptors. A specific compound of the present invention is 4-(4-aminobutyl)-1,3-dihydro-5-methyl-2H-imidazole-2-thione, hereinafter referred to as 4-(4-Aminobutyl)-5-methylimidazole-2-thione.

REFERENCES:
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Theilheimer Synthetic Methods of Organic Chemistry, vol. 8, 1954, p. 161.
Pyman, J. Chem. Soc., 98-100 (1930).
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Bullerwell et al., C.A., vol. 46, 9096F.
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Stanacev et al., Chem. Abst. 51:11995d, 61:13249a, 62:14577b, 64:3428e and 66:55478e.
Steglich et al., Angrew. Chem. Internat. Edit. 8:982 (1969).

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