2H-1-benzopyran derivatives processes for their preparation...

Details 2H-1-benzopyran derivatives processes for their preparation... 2H-1-benzopyran derivatives processes for their preparation...

2005-10-04

2005-10-04

Owens, Amelia A. (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S320000, C546S196000, C549S399000, C549S406000

Reexamination Certificate

active

06951883

ABSTRACT:
2H-1-Benzopyran derivatives, processes for their preparation and use thereof for the preparation of pharmaceutical compositions for the prevention and treatment of postmenopausal pathologies.

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Jacobsen et al Preparation of novel (+)-enantiomers of cis-3,4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes: CA 129:4580 (1998).
T.A. Grese et al.: “Structure-activity relationships of selective estrogen receptor modulators: modifications to the 2-arylbenzothiophene core of raloxifene” Journal of Medicinal Chemsitry, vol. 40, No. 2, pp. 146-167, Oct. 17, 1997.

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