2H-1,2-benzothiazine derivatives

Organic compounds -- part of the class 532-570 series – Organic compounds – Chalcogen in the nitrogen containing substituent

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C07D41704, A61K 3138

Patent

active

046940804

ABSTRACT:
Certain substituted-4-hydroxy-(or 4-acyloxy-)2H-1,2-benzothiazine 1,1-dioxides having at the 3-position a 2-substituted-1,3,4-oxadiazol-5-yl, a 2-substituted-tetrazol-5-yl or a 1-substituted-tetrazol-5-yl group useful as selective 5-lipoxygenase pathway inhibitors; and methods for their preparation.

REFERENCES:
patent: 3303189 (1967-02-01), Loeu
patent: 3957772 (1976-05-01), Fabian et al.
E. P. 115-748-A (Abstract) 8/15/84.
Shen et al., "The Development of Antiasthmatic Drugs", Butterworth Publishers, Kent, England, pp. 316-317 and 331-335.

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