27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002,...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving oxidoreductase

Reexamination Certificate

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C435S190000

Reexamination Certificate

active

07867729

ABSTRACT:
The invention provides isolated nucleic acids molecules, designated 27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 and 65577 nucleic acid molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 and 65577 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 or 65577 gene has been introduced or disrupted. The invention still further provides isolated 27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 or 65577 proteins, fusion proteins, antigenic peptides and anti-27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 or 65577 antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided.

REFERENCES:
patent: 6136599 (2000-10-01), Cho
patent: 00863 (2002-01-01), None
Cook el al. Isolation and characterization of cDNA clones for rat liver 10-formyltetrahydrofolate dehydrogenase. J. Biol. Chem. 266 (8), 4965-4973 (1991).
Meyers et al., Geneseq database accession No. ABB08241, Apr. 2002, see hit #1 in the attcahed Geneseq search results.
Cook. R. J., et al, “Isolation and Characterization of cDNA Clones for Rat Liver 10-Formyltetrahydrofolate Dehydrogenase,”The Journal of Biological Chemistry, Mar. 15, 1991, pp. 1965-1973, vol. 266, No. 8.
Hong, M. et al., “Isolation and Characterization of cDNA Clone for Human liver 10-Pormyltetrahydrofolate Dehydrogenase,”Biochemistry and Molecular Biology International, Mar. 1999, pp. 407-415, vol. 47, No. 3.
Yoshida, A., et al., “Human Aldehyde Dehydrogenase Gene Family,”European Journal of Biochemistry, Feb. 1998, pp. 549-557, vol. 251, No. 3.
EMBL Database Report for Accession No. AA424371, 1997 Unpublished (XP-002212692).
EMBL Database Report for Accession No. AF052732, Sep. 21, 1998 (XP-002212693).
EMBL Database Report for Accession No. M59861, May 1, 1991 (XP-002212694).

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