27411, a novel human PGP synthase

Details 27411, a novel human PGP synthase 27411, a novel human PGP synthase

2006-06-13

2006-06-13

Achutamurthy, P. (Department: 1652)

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Transferase other than ribonuclease

C435S015000, C435S004000, C435S006120, C435S252300, C435S320100, C435S069100, C536S023200, C536S023500, C514S789000

Reexamination Certificate

active

07060476

ABSTRACT:
The present invention relates to a newly identified human PGP synthase. The invention also relates to polynucleotides encoding the PGP synthase. The invention further relates to methods using the PGP synthase polypeptides and polynucleotides as a target for diagnosis and treatment in PGP synthase-mediated or -related disorders. The invention further relates to drug-screening methods using the PGP synthase polypeptides and polynucleotides to identify agonists and antagonists for diagnosis and treatment. The invention further encompasses agonists and antagonists based on the PGP synthase polypeptides and polynucleotides. The invention further relates to procedures for producing the PGP synthase polypeptides and polynucleotides.

REFERENCES:
patent: WO01/02568 (2001-01-01), None
Chang, S.C., et al., “The PELI Gene (Renamed PGSI) Encodes the Phosphatidylglycero-Phosphate Synthase ofSaccharomyces cerevisiae, ” The Journal of Biochemical Chemistry, Apr. 17, 1998, pp. 9829-9836, vol. 273(16).
Gopalakrishnan, A.S., et al., “Structure and Expression of the Gene Locus Encoding the Phosphatidylglycerophosphate Synthase ofEscherichia coli,” The Journal of Biological Chemistry, Jan. 25, 1986, pp. 1329-1338, vol. 261(3).
Kawasaki, K., et al., “Isolation of a Chinese Hamster Ovary (CHO) cDNA Encoding Phosphatidylglycerophosphate (PGP) Synthase, Expression of Which Corrects the Mitochondrial Abnormalities of a PGP Synthase-Defective Mutant of CHO-K1 Cells,”The Journal of Biological Chemistry, Jan. 15, 1999, pp. 1828-1834, vol. 274(3).
BIOSIS Database Report for Accession No. PREV197866057954, 1978 (XP002180326).

Affiliated with

Also associated with

Rating

27411, a novel human PGP synthase does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 27411, a novel human PGP synthase, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 27411, a novel human PGP synthase will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3660742