Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving hydrolase
Reexamination Certificate
2006-05-02
2006-05-02
Prouty, Rebecca E. (Department: 1652)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving hydrolase
C435S195000, C435S325000, C530S350000, C536S023200
Reexamination Certificate
active
07037671
ABSTRACT:
The present invention relates to a newly identified human agmatinase-like arginase, designated “25312”. The invention also relates to polynucleotides encoding the agmatinase-like arginase. The invention further relates to methods using the agmatinase-like polypeptides and polynucleotides as a target for diagnosis and treatment in disorders mediated by or related to the agmatinase-like arginase. The invention further relates to drug-screening methods using the polypeptides and polynucleotides to identify agonists and antagonists for diagnosis and treatment. The invention further encompasses agonists and antagonists based on the polypeptides and polynucleotides. The invention further relates to agonists and antagonists identified by drug screening methods with the polypeptides and polynucleotides as a target.
REFERENCES:
patent: 5912159 (1999-06-01), Vockley et al.
patent: 6413757 (2002-07-01), Cook et al.
patent: 0 679 716 (1995-11-01), None
patent: WO 01/02568 (2001-01-01), None
Satishchandran, et al., “Purification and Properties of Agmatine Ureohydrolyase, A Putrescine Biosynthetic Enzyme inEscherichia coli,” Journal of Bacteriology, vol. 165 (4), (Mar. 1986), pp. 843-848, American Society for Microbiology.
Strausberg, Robert, 'wc29b04.x1 NCI_CGAP_Kid11 Homo sapiens cDNA Clone IMAGE:2316559 3′ Similar to SW:SPEB_ECOLI P16936 Agmatinase:, mRNA Sequence, May 18, 1999, (sequence) GenBank [online]Bethesda, MD, USA: National Center for Biotechnology Information [retrieved on Jul. 10, 2001]. Retrieved from the Internet: URL: http://www.ncbi.nlm.nih.gov/>. GenBank Accession No. AI671332.
Strausberg, Robert, “ti28e10.x1 NCI_CGAP_Kid11 Homo sapiens cDNA Clone IMAGE:2131818 3′ Similar to Contains PTR7 Repetitive Element:, mRNA Sequence,” Mar. 11, 1999, (sequence) GenBank [online] Bethesda, MD, USA: National Center for Biotechnology Information [retrieved on Jul. 10, 2001]. Retrieved from the Internet: URL: http://www.ncbi.nlm.nih.gov/>. GenBank Accession No. AI492488.
Strausberg, Robert, “td12b02.x1 NCI_CGAP_Co16 Homo sapiens cDNA Clone IMAGE:2075403 3′ Similar to SW:SPEB_ECOLI P16936 Agmatinase:, mRNA Sequence,” Jul. 12, 1999, (sequence) GenBank [online] Bethesda, MD, USA: National Center for Biotechnology Information [retrieved on Jul. 10, 2001]. Retrieved from the Internet: URL: http://www.ncbi.nlm.nih.gov/>. GenBank Accession No. AI832076.
Strausberg, Robert, “xm71b12.x1 NCI_CGAP_Kid11 Homo sapiens cDNA Clone IMAGE:2689631 3′ Similar to SW:SPEB_STRCL P37819 Possible Agmatinase;, mRNA Sequence,” Dec. 15, 1999, (sequence), EMBL Database [online], Hinxton, Cambridge, U.K., European Bioinformatics Institute, [retrieved on Nov. 15, 2001]. Retrieved from the Internet: URL: http://www.ebi.ac.uk/embl/>. EMBL Accession No. AW237392.
Strausberg, Robert, “tq96f12.x1 NCI_CGAP_Ov23 Homo sapiens cDNA Clone IMAGE:2216687 3′ Similar to SW:SPEB_ECOLI P16936 Agmatinase; Contains PTR7.b3 PTR7 Repetitive Element;, mRNA Sequence,” May 5, 1999, (sequence), EMBL Database [online], Hinxton, Cambridge, U.K., European Bioinformatics Institute, [retrieved on Nov. 15, 2001]. Retrieved from the Internet: URL: http://www.ebi.ac.uk/embl/>. EMBL Accession No. AI653589.
Mistry, S.J. et al., “Cloning and Tissue-Specific Expression of Mammalian Agmatinase: A Potential Regulator of Agmatine Effects on Glomerular Filtration and Cell Proliferation in Renal Inflammation,”Journal of the American Society of Nephrology, vol. 10, (Sep. 1999), Abstract No. A1938.
Cook William James
Curtis Rory A. J.
Spaltmann Frank
Bayer Corporation
Millennium Pharmaceuticals Inc.
Millennium Pharmaceuticals Inc.
Prouty Rebecca E.
Walicka Malgorzata A.
LandOfFree
25312, a novel human agmatinase-like homolog does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with 25312, a novel human agmatinase-like homolog, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 25312, a novel human agmatinase-like homolog will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3524970