25-Substituted-5.alpha.-cholestane-3.beta.,22S-diol

Details 25-Substituted-5.alpha.-cholestane-3.beta.,22S-diol 25-Substituted-5.alpha.-cholestane-3.beta.,22S-diol

1981-11-09

1982-09-07

Roberts, Elbert L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07J 900

Patent

active

043483283

ABSTRACT:
25-Substituted-5.alpha.-cholestane-3.beta.,22S-diols and esters thereof of Formula I which inhibit the activity of 3-hydroxy-3-methyl-glutaryl coenzyme A reductase and inhibit the formation of serum cholesterol are disclosed.

REFERENCES:
patent: 4193930 (1980-03-01), Chorvat
patent: 4205004 (1980-05-01), Chorvat
patent: 4230626 (1980-10-01), Chorvat
patent: 4299774 (1981-10-01), Chorvat

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