25-methylene and 24-25 -epoxy marcfortines and paraherquamides

Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...

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C07D24136

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active

058861807

ABSTRACT:
The present invention are marefortines and paraherquamides where the 7-member oxygenated ring has been modified to produce 25-methylene compounds (VII) and 24,25-epoxy compounds (VIII) all of which are useful as antiparasitic agents against endo and ecto parasites, particularly helminths and arthropods.

REFERENCES:
patent: 4866060 (1989-09-01), Mrozik
patent: 4873247 (1989-10-01), Goegelman et al.
patent: 4923867 (1990-05-01), Blizzard et al.
patent: 4978656 (1990-12-01), Blizzard et la.
patent: 5703078 (1997-12-01), Lee
J. Chem. Soc. Chem. Communications, pp. 601-602 (1980).
Tetrahedron Letters, 22, pp. 1977-1980 (1980).
Tetrahedron Letters, 22, pp. 135-136 (1981).
J. of Antibiotics, 44, pp. 492-497 (1991).
J. of Antibiotics, 43, pp. 1380-1386 (1990).
J. Am. Chem. Soc., 118, 3, pp. 557-579 (1996).
J. Am. Chem. Soc., 115, 20, pp. 9323-9324 (1993).

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