25, 28-dihydroxyergocalciferol and 1,25,28-trihydroxyergocalcife

Details 25, 28-dihydroxyergocalciferol and 1,25,28-trihydroxyergocalcife 25, 28-dihydroxyergocalciferol and 1,25,28-trihydroxyergocalcife

1988-11-14

1990-05-29

Lipovsky, Joseph A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

9,10-seco- cyclopentanohydrophenanthrene ring system doai

552653, A61K 3159, C07J 900

Patent

active

049296094

ABSTRACT:
Compounds of the formula ##STR1## wherein R" is hydrogen or hydroxy, epimers at the 24-position of compounds of formula I, diastereomeric mixtures of compounds of formula I which are epimeric at the 24-position, and mixtures thereof, which are useful as agents for the treatment of psoriasis, and osteoporosis, are described.

REFERENCES:
patent: 4012509 (1977-03-01), Frank
patent: 4069321 (1978-01-01), Jones et al.
Methods In Enzymology, vol. 123 (1986) p. 127-140; Napoli et al.

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