25,26-dehydro-1.alpha.,24R-dihydroxycholecalciferol and 25,26-de

Details 25,26-dehydro-1.alpha.,24R-dihydroxycholecalciferol and 25,26-de 25,26-dehydro-1.alpha.,24R-dihydroxycholecalciferol and 25,26-de

1984-11-29

1986-06-10

Roberts, Elbert L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

9,10-seco- cyclopentanohydrophenanthrene ring system doai

2603972, C07J 900

Patent

active

045943400

ABSTRACT:
The syntheses of 25,26-dehydro-1.alpha.,24R-dihydroxycholecalciferol and 25,26-dehydro-1.alpha.,24S-dihydroxycholecalciferol and the epimeric mixture which are useful as differentiation inducing agent and anti-proliferation agents are described. 25,26-dehydro-1.alpha.,24R-dihydroxycholecalciferol, 25,26-dehydro-1.alpha.,24S-dihydroxycholecalciferol, and the epimeric mixture are useful in treating osteoporosis, tumors and leukemia.

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