Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – 9,10-seco- cyclopentanohydrophenanthrene ring system doai
Patent
1984-11-29
1986-09-16
Roberts, Elbert L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
9,10-seco- cyclopentanohydrophenanthrene ring system doai
2603972, 568379, 568664, A61K 3159
Patent
active
046123083
ABSTRACT:
The syntheses of 25,26-dehydro-1.alpha.,23S-dihydroxycholecalciferol, 25,26-dehydro-1.alpha.,23R-dihydroxycholecalciferol, and the epimeric mixture thereof which are useful as differentiation inducing agents and anti-proliferation agents are described, 25,26-dehydro-1.alpha.,23S-dihydroxycholecalciferol 25,26-dehydro-1.alpha.,23R-dihydroxycholecalciferol and the epimeric mixture thereof are useful for treating tumors and leukemia, and osteoporosis.
REFERENCES:
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Baggiolini Enrico G.
Truitt Gary A.
Uskokovic Milan R.
Wovkulich Peter M.
Boxer Matthew
Hoffmann-La Roche Inc.
Leon Bernard S.
Roberts Elbert L.
Saxe Jon S.
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