Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1987-03-06
1989-12-12
Hollrah, Glennon H.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
549264, A61K 31335, C07D31396
Patent
active
048868299
ABSTRACT:
The present invention relates to novel 23-oxo (keto) and 23-imino derivatives of certain C(26,27)-epoxy- and C(14,15;26,27)-diepoxy-LL-F28249 compounds. The LL-F28249 compounds (collectively) are isolates from the fermentation broth of Streptomyces cyaneogriseus subspecies noncyanogenus having deposit accession no. NRRL-15773. The derivatives are obtained by oxidation of the 23-hydroxy group of 5-O-silylated-C(26,27)-epoxy and C(14,15;26,27)diepoxy-LL-F28249 compounds, followed by desilylation and derivatization with amino compounds. The novel compounds have anthelmintic, ectoparasiticidal, nematicidal, insecticidal and acaricidal activity and are, therefore, useful in the treatment of infections in warm-blooded animals and infestations in agricultural crops. Compositions containing the present compounds as active ingredients thereof also are presented.
REFERENCES:
patent: 4201861 (1980-05-01), Mrozik et al.
patent: 4289760 (1981-09-01), Mrozik et al.
patent: 4423209 (1983-12-01), Mrozik
patent: 4530921 (1985-07-01), Mrozik
patent: 4547520 (1985-10-01), Ide et al.
patent: 4579864 (1986-04-01), Linn et al.
patent: 4696922 (1987-09-01), Sturm et al.
Asato Goro
Tamura Susan Y.
American Cyanamid Company
Hollrah Glennon H.
Trinh Ba
Tsevdos Estelle J.
LandOfFree
23-Oxo (keto) and 23-imino derivatives of mono- and diepoxy LL-F does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with 23-Oxo (keto) and 23-imino derivatives of mono- and diepoxy LL-F, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 23-Oxo (keto) and 23-imino derivatives of mono- and diepoxy LL-F will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2121964