22-Hydroxy derivatives of C-076 compounds, pharmaceutical compos

Details 22-Hydroxy derivatives of C-076 compounds, pharmaceutical compos 22-Hydroxy derivatives of C-076 compounds, pharmaceutical compos

1981-08-28

1983-11-01

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Conjugate or complex of monoclonal or polyclonal antibody,...

Conjugated via claimed linking group, bond, chelating agent,...

424181, 435 76, 536 71, A61K 3171, C07H 1708, C12P 1962

Patent

active

044129912

ABSTRACT:
There is disclosed novel derivatives of C-076 compounds wherein the 22-position, normally substituted, is substituted with a hydroxy group. The compounds are isolated from the C-076 fermentation broth of Streptomyces avermitilis. The compounds have potent anthelmintic, insecticidal, and acaricidal activity and compositions for that use are also disclosed.

REFERENCES:
patent: 4199569 (1980-04-01), Chabala et al.
patent: 4206205 (1980-06-01), Mrozik et al.

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