2150, human protein kinase family member and uses therefor

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Transferase other than ribonuclease

Reexamination Certificate

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C530S350000, C435S252300, C435S320100, C435S006120

Reexamination Certificate

active

11713844

ABSTRACT:
The invention provides isolated nucleic acids molecules, designated 2150 nucleic acid molecules, which encode novel protein kinase family members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 2150 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 2150 gene has been introduced or disrupted. The invention still further provides isolated 2150 proteins, fusion proteins, antigenic peptides and anti-2150 antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided.

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Ishida, N., “Homo sapiens Pim-2h, hUGT2, hUGT1, genes for pim-2 protooncogene homolog, UDP-galactose transporter 1, UDP-galactose transporter 2, complete cds,” May 11, 2000 (sequence), EMBL [on line] Hinxton Cambridge UK: European Bioinformatics Institute (retrieved on Jul. 6, 2005), EMBL accession No. AB042425.
Strausberg R., “Homo sapiens, pim-2 oncogene, clone MGC:8925 IMAGE:3913552, mRNA, complete cds.” Dec. 6, 2001 (sequence) GenBank [online] Bethesda, MD, USA: National Center for Biotechnology Information [retrieved on Aug. 19, 2002]. Retrieved from the Internet: URL: http://www.ncbi.nlm.nih.gov/>. GenBank Accession No. BC018111.
Baytel, D., et. al., “Human pim-2 protooncogene homolog pim-2h mRNA, complete cds.” Nov. 20, 1998 (sequence) GenBank [online] Bethesda, MD, USA: National Center for Biotechnology Information [retrieved on Aug. 19, 2002]. Retrieved from the Internet: URL: http://www.ncbi.nlm.nih.gov/>. GenBank Accession No. U77735.

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