2150, human protein kinase family member and uses therefor

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving transferase

Reexamination Certificate

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C435S252300, C435S320100, C435S194000, C435S006120

Reexamination Certificate

active

06911317

ABSTRACT:
The invention provides isolated nucleic acids molecules, designated 2150 nucleic acid molecules, which encode novel protein kinase family members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 2150 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 2150 gene has been introduced or disrupted. The invention still further provides isolated 2150 proteins, fusion proteins, antigenic peptides and anti-2150 antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided.

REFERENCES:
patent: 2003/0125231 (2003-07-01), Li et al.
Baytel et al., BBA, 1442, 274-285, 1998.
Strausberg R., “Homo sapiens,pim-2 oncogene, clone MGC:8925 IMAGE:3913552, mRNA, complete cds.” Dec. 6, 2001 (sequence) GenBank [online] Bethesda, MD, USA: National Center for Biotechnology Information [retrieved on Aug. 19, 2002]. Retrieved from the Internet: URL: http://www ncbi.nlm nih.gov/>. GenBank Accession No. BC018111.
Baytel, D., et. al., “Human pim-2 protooncogene homolog pim-2h mRNA, complete cds.” Nov. 20, 1998 (sequence) GenBank [online] Bethesda, MD. USA: National Center for Biotechnology Information [retrieved on Aug. 19, 2002]. Retrieved from the Internet: URL: http://www.ncbi.nlm.nih gov/>. GenBank Accession No. U77735.

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