21-alkyl-, cycloalkyl- or aryl-substituted thio steroids and pha

Details 21-alkyl-, cycloalkyl- or aryl-substituted thio steroids and pha 21-alkyl-, cycloalkyl- or aryl-substituted thio steroids and pha

1986-06-23

1989-08-29

Nigel, Floyd D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

514179, 2603971, 26039745, A61K 3157, C07J 700, C07J 3100, C61K 3156

Patent

active

048617652

ABSTRACT:
A 21-substituted thiosteroid represented by the general formula ##STR1## wherein R.sup.1 represents an alkyl group having 1 to 6 carbon atoms, a cycloalkyl group having 5 or 6 carbon atoms, a phenyl group, or a benzyl group which may have a substituent on the benzene ring,

REFERENCES:
patent: 3028400 (1962-04-01), Ruschig et al.
patent: 3105083 (1963-09-01), Lincoln et al.
patent: 3171844 (1965-03-01), Cross
patent: 4335121 (1982-06-01), Phillipps et al.
patent: 4427671 (1984-01-01), Torossian et al.
patent: 4488995 (1984-12-01), Varma
Bordwell et al., J. Amer. Chem. Soc., vol. 73, p. 5004 (1951).
Shirley et al., J. Amer. Chem. Soc., vol. 73, pp. 4885 to 4886 (1951).
Theilheimer, "Synthetic Methods of Organic Chemistry", vol. 16, p. 52, #107 (1962).

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