20-Oxo-pregnacalciferol analogs with binding affinity to the pro

Details 20-Oxo-pregnacalciferol analogs with binding affinity to the pro 20-Oxo-pregnacalciferol analogs with binding affinity to the pro

1995-10-05

1997-03-25

Criares, Theodore J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

9,10-seco- cyclopentanohydrophenanthrene ring system doai

552653, A61K 3159, C07C 300

Patent

active

056145128

ABSTRACT:
A birth control method for a female mammal which comprises administering to the mammal an amount of a vitamin D compound sufficient to block binding of progesterone to the progesterone receptor in said mammal. The vitamin D compounds are 20-oxo-pregnacalciferol analogs, preferably 3-desoxy-20-oxo-19-nor-pregnacalciferol and its 2-oxo analog.

REFERENCES:
patent: 5397776 (1995-03-01), DeLuca et al.

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