20-keto-11.beta.-arylsteroids and their derivatives having agoni

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Cyclopentanohydrophenanthrene ring system doai

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Details

540107, 540108, 514841, 514843, A61K 3158, C07J 4300

Patent

active

060203285

ABSTRACT:
The invention is directed to 20-keto-11.beta.-arylsteroids of formula I: ##STR1## wherein R.sup.1, R.sup.6, R.sup.7, R.sup.9, R.sup.12 and X are as defined by the specification. The compounds exhibit progestational and antiprogestational activities.

REFERENCES:
patent: 4386085 (1983-05-01), Teutsch et al.
patent: 4447424 (1984-05-01), Teutsch et al.
patent: 4609651 (1986-09-01), Rohde et al.
patent: 4774236 (1988-09-01), Cook et al.
patent: 4861763 (1989-08-01), Cook et al.
patent: 4871724 (1989-10-01), Groen et al.
patent: 4874754 (1989-10-01), Nique et al.
patent: 4900725 (1990-02-01), Nioue et al.
patent: 4954490 (1990-09-01), Cook et al.
patent: 5073548 (1991-12-01), Cook et al.
patent: 5446036 (1995-08-01), Scholz et al.
Chemical Abstract, AN 78501u, EP 299,913, Jan. 18, 1989.
Chemical Abstract, AN 6285s, FR 2,586,021, Feb. 13, 1987.
Chemical Abstract, AN 154227b, EP 308,345, Mar. 22, 1989.
Chemical Abstract, AN 164959b, EP 310,542, Apr. 5, 1989.
Chemical Abstract, AN 132580a, EP 369,881, May 23, 1990.
Chemical Abstract, AN 93429d, DE 3,621,024, Dec. 23, 1987.
Patent Abstract of US 4,477,445, Oct. 16, 1994.
G. Teutsch, et al., Human Reproduction, vol. 9, Supplement 1, pp. 12 to 31, "History and Perspectives of Antiprogestins from the Chemist s Point of View", 1994.
C. E. Cook, et al., Human Reproduction, vol. 9, Supplement 1, pp. 32 to 39, "Effects of D-Ring Substituents on Antiprogestational (Antagonist) and Progestational (Agonist) Activity of 11.beta.-aryl steroids", 1994.
M. J. van den Heuvel, et al., Recueil des Travaux Chimiques des Pays-Bas., vol. 112, No. 02, pp. 107 to 112, "Synthesis of 6.beta.-Methyl Analogues of Mifepristone, New Selective Antiprogestagens", 1993.

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