20'-Hydroxyvinblastine and related compounds

Details 20'-Hydroxyvinblastine and related compounds 20'-Hydroxyvinblastine and related compounds

1980-12-29

1982-03-16

Daus, Donald G.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424262, C07D51904, A61K 31475

Patent

active

043200583

ABSTRACT:
20'-Hydroxy derivatives of VLB, leurosidine and vincristine, antimitotic agents.

REFERENCES:
patent: 4029663 (1977-04-01), Gutowski et al.
patent: 4110330 (1978-08-01), Barnett et al.
Barnett et al., J. Med. Chem., 21, 88, (1978).
Conrad et al., id, 22, 391, (1979).
Kutney et al., Can. J. Chem., 56, 42, (1974).
Kutney et al., Heterocycles, 6, 905, (1977).
Kutney et al., id, 3, 639, (1975).
Kutney et al., id, 3, 205, (1975).
Potier et al., J.C.S. Chem. Comm., 670, (1975).
Potier et al., J.A.C.S., 101, 2243, (1979).

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