20-Hydroperoxy cholesterol compounds for suppression of atheroge

Details 20-Hydroperoxy cholesterol compounds for suppression of atheroge 20-Hydroperoxy cholesterol compounds for suppression of atheroge

1988-10-26

1990-02-13

Lipovsky, Joseph A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

2603972, A61K 3156, C07J 900

Patent

active

049007262

ABSTRACT:
A method is provided for suppressing atherogenesis in which a cholesterol 20-hydroperoxide is administered, which is preferably one or both of the novel compounds: 20(R)-hydroperoxy-25-hydrocholesterol and 29(S)-hydroperoxy-25-hydrocholesterol.

REFERENCES:
patent: 4789670 (1988-12-01), Tipton et al.
Chemical Abstracts; vol. 107 (1987), #168497u; Tipton et al.
Chemical Abstracts; vol. 106 (1987), #31761k; Highley et al.

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