20-Amino tylosin derivatives and pharmaceutical compositions con

Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,... – Conjugated via claimed linking group – bond – chelating agent,...

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536 71, A61K 3171, C07H 1508

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active

044407599

ABSTRACT:
20-Amino derivatives of tylosin and desmycosin are active against bacteria and Mycoplasma.

REFERENCES:
patent: 3178341 (1965-04-01), Hamill et al.
patent: 4196280 (1980-04-01), Umezawa et al.
patent: 4279896 (1981-07-01), Ganguly et al.
patent: 4345069 (1982-08-01), Sakakibara et al.
H. Matsubara et al., "Chemical Transformation of Tylosin, a 16-Membered Macrolide, and Its Structure-Activity Relationship", Chem. Pharm. Bull. 30 (1), 97-110 (1982).
S. Omura et al., "Novel Dimeric Derivatives of Leucomycins and Tylosin, Sixteen-Membered Macrolides", J. Med. Chem. 25, 271-275 (1982).
Derwent Abstract No. 71396Y of Japanese Unexamined Patent 2100-485 (Takeda), Aug. 23, 1977.
S. Satoi et al., "Mycinamicins, New Macrolide Antibiotics. I: Taxonomy, Production, Isolation Characterization and Properties", J. Antibiotics 33 (4), 364-377, (1980).
Derwent Abstract No. 92092A/51 of Japanese Unexamined Patent 3130-686 (Toyo Brewing), Nov. 14, 1978.
Derwent Abstract No. 008688/01 of Japanese Unexamined Patent 3132-584 (Toyo Brewing) Nov. 18, 1978.
Derwent Abstract No. 65537B/36 of Japanese Unexamined Patent 4095-584 (Toyo Brewing) Jul. 28, 1979.

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