2′-terminator nucleotide-related methods and systems

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Reexamination Certificate

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C435S975000, C536S022100

Reexamination Certificate

active

07572581

ABSTRACT:
The present invention provides methods of extending primer nucleic acids and sequencing target nucleic acids. The methods include the use of 2′-terminator nucleotides to effect chain termination. In addition to related reaction mixtures and kits, the invention also provides computers and computer readable media.

REFERENCES:
patent: 4458066 (1984-07-01), Caruthers et al.
patent: 4469863 (1984-09-01), Ts'o et al.
patent: 4594320 (1986-06-01), Fujishima
patent: 5034506 (1991-07-01), Summerton et al.
patent: 5216141 (1993-06-01), Benner
patent: 5235033 (1993-08-01), Summerton et al.
patent: 5386023 (1995-01-01), Sanghvi et al.
patent: 5532130 (1996-07-01), Alul et al.
patent: 5547835 (1996-08-01), Koster
patent: 5602240 (1997-02-01), De Mesmaeker et al.
patent: 5637684 (1997-06-01), Cook et al.
patent: 5644048 (1997-07-01), Yau
patent: 5928906 (1999-07-01), Koster et al.
patent: 5939292 (1999-08-01), Gelfand et al.
patent: 5990303 (1999-11-01), Seela
patent: 6495671 (2002-12-01), Manoharan et al.
patent: 6699668 (2004-03-01), Schmidt et al.
patent: 2001/0041794 (2001-11-01), Bischofberger et al.
patent: 2007/0154914 (2007-07-01), Gelfand et al.
patent: 2007008997 (2007-10-01), None
patent: WO 9913103 (1999-03-01), None
patent: WO 00/63366 (2000-10-01), None
patent: WO 01/90121 (2001-11-01), None
patent: WO 02/057425 (2002-07-01), None
patent: 2005005667 (2005-01-01), None
patent: 2005005667 (2005-01-01), None
patent: 2005118608 (2005-12-01), None
patent: 2005118608 (2005-12-01), None
patent: 2007075967 (2007-07-01), None
patent: 2007075967 (2007-07-01), None
Wu et al. “Studies of nucleotide binding to the ribonucleic acid polymerase by a fluorescence technique” Biochemistry. Nov. 1969;8(11):4450-8.
Carroll et al. (“Inhibition of hepatitis C virus RNA replication by 2′-modified nucleoside analogs” J Biol Chem. Apr. 4, 2003;278(14):11979-84. Epub Jan. 27, 2003).
Stratagene (“Gene Characterization Kits” 1988).
Carroll (“Inhibition of hepatitis C virus RNA replication by 2′-modified nucleoside analogs” J Biol Chem. Apr. 4, 2003;278(14):11979-84. Epub Jan. 27, 2003).
Hamel (“Interactions of guanosine triphosphate analogues with elongation factor G ofEscherichia coli” Eur J Biochem. Apr. 1, 1976;63(2):431-40).
Hamel (“Derivatives of guanosine triphosphate with ribose 2′-hydroxyl substituents. Interactions with the protein synthetic enzymes ofEscherichia coli” Eur J Biochem. Nov. 15, 1976;70(2):339-47).
Moore et al. (2002) “Synthesis of Nucleotide Analogues That Potently and Selectively Inhibit Humna DNA Primase.”Biochemistry41:14066-14075.
U.S. Appl. No. 60/519,661, filed Nov. 12, 2003, Gelfand et al.
Adams et al. (1969) “Nucleotide sequence from the coat protein cistron of R17 bacteriophage RNA.”Nature223(210): 1009-1014.
Beaucage and Iyer (1993) “The Functionalization of Oligonucleotides via Phosphoramidite Derivative.”Tetrahedron49(10): 1925-1963.
Beaucage and Caruthers (1981) “Deoxynucleoside Phosphoramidites—A New Class of Key Intermediates for Deoxypolynucleotide Synthesis.”Tetrahedron Letters. 22:1859-1862.
Brill et al. (1989) “Synthesis of Oligodeoxynucleoside Phosphorodithioates via Thioamid.”Journal of American Chemistry Society111:2321-2323.
Brown et al. (1979) “Chemical synthesis and Cloning of a Tyrosine tRNA Gene.”Methods in Enzymology68:109-151.
Brownlee et al. (1967) “Molecular Structure: Nucleotide Sequence of 5S-ribosomal RNA fromEscherichia coli.” Nature215(102): 735-736.
Carlsson et al. (1996) Screening for Genetic Mutations.Nature380:207.
Carroll et al. (2003) “Inhibition of Hepatitis C Virus RNA Replication by 2′-Modified Nucleoside Analogs.”The Journal of Biological Chemistry278(14): 11979-11984.
Denpcy et al. (1995) “Synthesis of a Thymidyl Pentamer of Deoxyribonucleic Guanidine and Binding Studies with DNA Homopolynucleotides.”Proceedings of the National Academy of Sciiences USA92: 6097-6101.
Egholm et al. (1992) “Peptide nucleic acids (PNA). Oligonucleotide analogs with an achiral peptide backbone.”al of American Chemistry Society114:1895-1897.
Egholm et al. (1993) “PNA hybridizes to complementary oligonucleotides obeying the Watson-Crick hydrogen-bonding rules.”Nature365:566-568.
Gao and Jeffs (1994) “Unusual conformation of a 3′-thioformacetal linkage in a DNA duplex.”Journal of Biomolecular NMR4:17-34.
Gilbert and Maxam (1973) The nucleotide sequence of the lac operatorProceedings of the National Academiy of Sciences USA70(12): 3581-3584.
Grein et al. (1994) “3-Deaza- and 7-Deazapurines: Duplex Stability of Oligonucleotides Containing Modified Adenine or Guanine Bases.”Bioorganic Medicinal Chemistry Letters4(8): 971-976.
Horn et al. (1996) Oligonucleotides with alternating anionic and cationic phosphoramidate linkages: Synthesis and hybridization of stereo-uniform isomers.Tetrahedron Letters37:743-764.
Jenkins and Turner (1995) “The Biosynthesis of Carbocyclic.”Chemical Society Review169-176.
Jung et al. (1994) “Hybridization of Alternating Cationic.Anionic Oligonucleotieds to RNA Segments.”Nucleoside&Nucleotide13(6&7):1597-1605.
Kiedrowski et al. (1991) “Parabolic Growth of a Self-Replicating Hexadeoxynucleotide Bearing a 3′-5′-Phosphamidate Linkage.”Angew. Chem. Int. Ed. English30: 423-426.
Lee et al. (1992) “DNA sequencing with dye-labeled terminators and T7 DNA polymerase: effect of dyes and dNTPs on incorporation of dye-terminators and probability analysis of termination fragments,”Nucleic Acid Res. 20:2471-2483.
Letsinger (1970) “Phosphoramidate Analogs of Oligonucleotides.”Journal of Organic Chemistry35(11): 3800-3803.
Letsinger et al. (1986) “Effects of pendant groups at phosphorus on binding properties of d-ApA analogues.”Nucleic Acids Research14: 3487-3499.
Letsinger et al. (1988) “Cationic oligonucleotides.”Journal of American Chemistry Society10:4470-4471.
Mag et al. (1991) “Synthesis and selective cleavage of an oligodeoxynucleotide containing a bridged internucleotide 5′-phosphorothioate linkage.”Nucleic Acids Research19(7):1437-1441.
Matteucci et al. (1981) “Total solid-phase synthesis of porcine gut gastrin releasing peptide (GRP), a mammalian bombesin.”Journal of American Chemistry Society103:3185-3191.
Maxam and Gilbert (1977) A new method for sequencing DNAProceedings of the National Academy of Sciences USA74:560-564.
Meier and Engles (1992) “Peptide Nucleic Acids (PNAs)—Unusual Properties of Nonionic Oligonucleotide Analogues.”Angew. Chem. Int. Ed. English31(8):1008-1010.
Mesmaeker et al. (1994) “Comparison of Rigid and Flexible Backbones in Antisense Oligonucleotides.”Bioorganic&Medicinal Chemistry Letters4(3): 395-398.
Narang et al. (1979) “Improved Phosphotriester Method for the Synthesis of Gene Fragments.”Methods in Enzymology68:90-99.
Pauwels et al. (1986) “Biological Activity of New 2-5A Analogues.”Chemica Scripta26: 141-145.
Sanger et al. (1973) “Use of DNA polymerase I primed by a synthetic oligonucleotide to determine a nucleotide sequence in phage fl DNA,”Proceedings of the National Academy of Sciences USA70(4): 1209-1213.
Sanger et al. (1977) “DNA sequencing with chain-terminating inhibitors,”Proceedings of the National Academy of Sciences USA(74)12: 5463-5467.
Sanger et al. (1992) “DNA sequencing with chain-terminating inhibitors,”Milestones in Biotechnologypp. 104-108.
Sanghvi and Cook (1994) ASC Symposium Series 580, “Carbohydrate Modifications in Antisense Research”, Ed. Chapters 2 and 3.
Sauer et al. (2002) “Facile method for automated genotyping of single nucleotide polymorphisms by mass spectrometry,”Nucleic Acids Resear

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