2′-hydroxyl group-modified ribonucleoside derivatives

Details 2′-hydroxyl group-modified ribonucleoside derivatives 2′-hydroxyl group-modified ribonucleoside derivatives

2007-03-08

2011-10-18

Lewis, Patrick (Department: 1623)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C536S022100, C536S023100, C536S025310, C536S025500

Reexamination Certificate

active

08039611

ABSTRACT:
Provided is a ribonucleoside derivative represented by General Formula (I):(wherein R1represents a hydrogen atom or the like, R2represents a hydrogen atom or the like, R3represents a methyl group or the like, and B represents a nucleic acid base residue optionally having a protecting group or a modifying group). An RNA containing this ribonucleoside derivative shows excellent hybridization ability and resistance to nuclease.

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