2-trialkylsilyl-3-furaldehydes

Details 2-trialkylsilyl-3-furaldehydes 2-trialkylsilyl-3-furaldehydes

1992-10-28

1994-06-21

Ivy, C. Warren

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D30746, C07D30748

Patent

active

053229533

ABSTRACT:
Anti-inflammatory 4-substituted 2-furanones are made from intermediates having the formula ##STR1## where R.sub.1, R.sub.2 and R.sub.3 independently are n-or branched chain alkyl of 1 to 6 carbons. These compounds can be used as intermediates to produce 4-substituted 2-furanones which are anti-inflammatory agents.

REFERENCES:
patent: 4500520 (1985-02-01), Haber
patent: 4935530 (1990-06-01), Lee
Goldsmith, et al., "Tetrahedron Letters", vol. 24, No. 52, 1983, pp. 5835-5838.
Katsumura, et al., "Tetrahedron Letters", vol. 26, No. 38, 1985, pp. 4625-4628.
Bures, et al., "Tetrahedron Letters", vol. 28, No. 48, 1987, pp. 5965-5968.
Bures, et al., "Tetrahedron Letters", vol. 29, No. 11, 1988, pp. 1247-1250.

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